Gene name:
OLIG2 (BHLHB1;BHLHE19;PRKCBP2;RACK17) ;
Protein name:
Oligodendrocyte transcription factor 2 (Oligo2) ;
Alternative:
Class E basic helix-loop-helix protein 19 (bHLHe19) ;Class B basic helix-loop-helix protein 1 (bHLHb1) ;Protein kinase C-binding protein RACK17 ;Protein kinase C-binding protein 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with NKX2-2.
Function:
Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.
Subcellular Location:
Nucleus
Cytoplasm
The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2.
Protein Attributes:
50:
MDSDASLVSS | RPSSPEPDDL | FLPARSKGSS | GSAFTGGTVS | SSTPSDCPPE |
100:
LSAELRGAMG | SAGAHPGDKL | GGSGFKSSSS | STSSSTSSAA | ASSTKKDKKQ |
150:
MTEPELQQLR | LKINSRERKR | MHDLNIAMDG | LREVMPYAHG | PSVRKLSKIA |
200:
TLLLARNYIL | MLTNSLEEMK | RLVSEIYGGH | HAGFHPSACG | GLAHSAPLPA |
250:
ATAHPAAAAH | AAHHPAVHHP | ILPPAAAAAA | AAAAAAAVSS | ASLPGSGLPS |
300:
VGSIRPPHGL | LKSPSAAAAA | PLGGGGGGSG | ASGGFQHWGG | MPCPCSMCQV |
323:
PPPHHHVSAM | GAGSLPRLTS | DAK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Mouse
ELISA Kit for Human Oligo2
ELISA Kit for Human Oligo2
ELISA Kit for Human Oligo2
CLIA Kit for Human Oligo2
CLIA Kit for Human Oligo2
CLIA Kit for Human Oligo2
Polyclonal Antibody for Human Oligo2
Polyclonal Antibody for Human Oligo2
Polyclonal Antibody for Human Oligo2
Monoclonal Antibody for Human Oligo2
Monoclonal Antibody for Human Oligo2
Monoclonal Antibody for Human Oligo2
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY